The structures we live and work in are susceptible to quality and performance problems during construction and maintenance that can impact performance and may, in some cases, render them dangerous. Infrared thermography can provide remarkable, nondestructive information about construction details and building performance. This paper discusses the numerous applications for the technology currently being used to inspect building envelopes. These include validation of structural details, verification of energy performance (conduction and air leakage), location of moisture intrusion, and the identification of structural and system degradation of roofs and facades.